mzTab-M Documentation Hub
mzTab-M is the HUPO-PSI community standard for reporting mass spectrometry-based small molecule metabolomics and lipidomics results. It is designed to be compact, human-readable, and machine-parseable, enabling straightforward integration with downstream analysis pipelines and data repositories.
Highlights
Semantically enriched |
All identifiers, units, and controlled vocabulary terms are referenced via ontology entries from PSI-MS, ChEBI, and other community ontologies. |
Typed and structured |
Mandatory and optional fields are formally typed. The JSON schema and specification define every allowed value unambiguously. |
Validation profiles |
Results can be validated against tiered validation profiles that reflect the level of identification confidence, from feature-only through summary-level reporting. |
AI-ready |
Structured, ontology-anchored metadata makes mzTab-M files suitable for automated processing and integration into AI/ML pipelines without additional curation. |
MetaboLights submission |
mzTab-M can be used to create full local submissions in ISA-Tab and MAF format for MetaboLights, the EMBL-EBI repository for metabolomics experiments, using the mztabm2mtbls library. |
Cite
When you use mzTab-M 2.1 in your work, please cite:
TBD
When you use mzTab-M 2.0 in your work, please cite:
Nils Hoffmann, Joel Rein, Timo Sachsenberg, Jürgen Hartler, Kenneth Haug, Gerhard Mayer, Oliver Alka, Saravanan Dayalan, Jake T. M. Pearce, Philippe Rocca-Serra, Da Qi, Martin Eisenacher, Yasset Perez-Riverol, Juan Antonio Vizcaíno, Reza M. Salek, Steffen Neumann, and Andrew R. Jones mzTab-M: A Data Standard for Sharing Quantitative Results in Mass Spectrometry Metabolomics. Analytical Chemistry 2019, 91 (5), 3302–3310. DOI: 10.1021/acs.analchem.8b04310 | PubMed PMID: 30688441