About mzTab-M

The Format

mzTab-M is the community standard for reporting mass spectrometry-based small molecule metabolomics and lipidomics results. It was developed by the Metabolomics Working Group of the HUPO Proteomics Standards Initiative (PSI) and ratified as PSI standard in 2019.

The format extends the earlier mzTab 1.0 proteomics format to address the specific needs of metabolomics: multiple adduct forms of the same molecule, MS1-based identification, confidence level reporting, and structured linkage between summary, feature, and evidence rows.

The mzTab-M 2.1 Publication

The ratification of mzTab-M 2.1 as part of the HUPO-PSI Document Process was accompanied by a peer-reviewed publication in TODO

TBD

The mzTab-M 2.0 Publication

The ratification of mzTab-M 2.0 as part of the HUPO-PSI Document Process was accompanied by a peer-reviewed publication in Analytical Chemistry:

Nils Hoffmann, Joel Rein, Timo Sachsenberg, Jürgen Hartler, Kenneth Haug, Gerhard Mayer, Oliver Alka, Saravanan Dayalan, Jake T. M. Pearce, Philippe Rocca-Serra, Da Qi, Martin Eisenacher, Yasset Perez-Riverol, Juan Antonio Vizcaíno, Reza M. Salek, Steffen Neumann, and Andrew R. Jones mzTab-M: A Data Standard for Sharing Quantitative Results in Mass Spectrometry Metabolomics. Analytical Chemistry 2019, 91 (5), 3302–3310. DOI: 10.1021/acs.analchem.8b04310 | PubMed PMID: 30688441

HUPO-PSI

The Human Proteome Organization Proteomics Standards Initiative develops open, community-driven data standards for proteomics and metabolomics. mzTab-M is one of a family of PSI formats that includes mzML, mzIdentML, mzQuantML, and others.

The PSI metabolomics working group is open to participation. See psidev.info/groups/metabolomics for contact details.